SCHEMBL29647453

SCHEMBL29647453

C[C@H](O)[C@@H](NC(=O)[C@H]1CCCN1C(=O)[C@@H](CCCCN)NC(=O)[C@@H](CO)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@H](N)CC(N)=O)C(=O)N[C@H](CC(=O)O)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H](Cc1ccc(O)cc1)C(=O)N[C@H](Cc1c[nH]cn1)C(=O)N[C@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ C5AR1 P21730 2/20 0.62
▸ CALCR P30988 4/20 0.58
▸ NPY2R P49146 7/20 0.58
▸ NPY4R P50391 7/20 0.58
▸ NPY5R Q15761 7/20 0.58
▸ NPY1R P25929 5/20 0.58
▸ MC4R P32245 1/20 0.58
▸ KDM1A O60341 1/20 0.58
▸ CRHR1 P34998 1/20 0.57
▸ CRHR2 Q13324 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30148163 1.00 C5AR1 (0.62) C5AR1CALCRNPY2RNPY4RNPY5R
SCHEMBL29637925 0.99 C5AR1 (0.63) C5AR1CALCRNPY2RNPY4RNPY5R
SCHEMBL30523596 0.98 C5AR1 (0.62) C5AR1CALCRNPY2RNPY4RNPY5R
SCHEMBL31386975 0.96 CALCR (0.63) C5AR1CALCRNPY2RNPY4RNPY5R
SCHEMBL30523581 0.95 CALCR (0.63) C5AR1CALCRNPY2RNPY4RNPY5R
SCHEMBL29637944 0.95 C5AR1 (0.65) C5AR1CALCRNPY2RNPY4RNPY5R
SCHEMBL31386983 0.94 C5AR1 (0.58) C5AR1CALCRNPY2RNPY4RNPY5R
SCHEMBL30432183 0.91 F2 (0.59) CALCRNPY2RNPY4RNPY5RNPY1R
SCHEMBL30436896 0.90 CALCR (0.68) C5AR1CALCRNPY2RNPY4RNPY5R
SCHEMBL29695646 0.89 NPY2R (0.63) C5AR1CALCRNPY2RNPY4RNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022148781-A1 COMBINATION OF MCOLN ACTIVATORS AND IMMUNE CHECKPOINT INHIBITORS INSTITUT CURIE (FR) 2022-07-14 — — WO claimed
WO-2026104809-A1 THERAPEUTIC BACTERIAL COMPOSITIONS Microbiotica Limited (GB) 2026-05-21 — — WO disclosed
WO-2026104810-A1 ISOLATED BACTERIA OR CULTURE SUPERNATANTS THEREOF FOR THE TREATMENT OF CANCER Microbiotica Limited (GB) 2026-05-21 — — WO disclosed
US-20230346850-A1 Therapeutic Bacterial Composition MICROBIOTICA LTD (GB) 2023-11-02 — — US disclosed
US-20230183297-A1 METHODS OF TREATMENT AND RELATED COMPOSITIONS ASCEND BIOPHARMACEUTICALS LTD (AU) 2023-06-15 — — US disclosed
EP-4153786-A1 THERAPEUTIC BACTERIAL COMPOSITION Microbiotica Limited (GB) 2023-03-29 — — EP disclosed
EP-4153787-A1 BACTERIAL BIOMARKER Microbiotica Limited (GB) 2023-03-29 — — EP disclosed
US-20230090495-A1 Bacterial Biomarker MICROBIOTICA LTD (GB) 2023-03-23 — — US disclosed
US-11505579-B2 Methods of treatment and related compositions ASCEND BIOPHARMACEUTICALS, INC. (AU) 2022-11-22 — — US disclosed
US-11439671-B2 Therapeutic bacterial composition Microbiotica Limited (GB) 2022-09-13 — — US disclosed
US-20220235097-A1 METHODS OF TREATMENT AND RELATED COMPOSITIONS ASCEND BIOPHARMACEUTICALS LTD (AU) 2022-07-28 — — US disclosed
WO-2022148781-A1 COMBINATION OF MCOLN ACTIVATORS AND IMMUNE CHECKPOINT INHIBITORS INSTITUT CURIE (FR) 2022-07-14 — — WO disclosed
US-11376285-B2 Bacterial biomarker Microbiotica Limited (GB) 2022-07-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11505579-B2 Methods of treatment and related compositions SMO, SHH, GLI1 C5AR1 843/4885CALCR 2108/4885NPY2R 2179/4885
US-20230183297-A1 METHODS OF TREATMENT AND RELATED COMPOSITIONS SMO, SHH, GLI1 C5AR1 843/4885CALCR 2108/4885NPY2R 2179/4885
US-20220235097-A1 METHODS OF TREATMENT AND RELATED COMPOSITIONS SMO, SHH, GLI1 C5AR1 843/4885CALCR 2108/4885NPY2R 2179/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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