Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.64 |
| ▸ | PARP11 | Q9NR21 | 4/20 | 0.64 |
| ▸ | PRCP | P42785 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 6/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4718535 | 1.00 | PARP10 (0.64) | PARP10PARP11PRCPPARP1BCHE | |
| SCHEMBL14785203 | 0.89 | PARP10 (0.51) | PARP10PARP11PRCPBCHEKDM4E | |
| SCHEMBL20539302 | 0.86 | NOTUM (0.47) | PARP10PARP11PARP1BCHEACHE | |
| SCHEMBL30916119 | 0.86 | NOTUM (0.47) | PARP10PARP11PARP1BCHEACHE | |
| SCHEMBL15312190 | 0.85 | PARP10 (0.47) | PARP10PARP11PRCPPARP1BCHE | |
| SCHEMBL31121854 | 0.85 | PARP10 (0.47) | PARP10PARP11PRCPPARP1BCHE | |
| SCHEMBL5871204 | 0.84 | PARP10 (0.46) | PARP10PARP11PARP1NOTUMHTR2C | |
| SCHEMBL10921073 | 0.81 | PARP10 (0.48) | PARP10PARP11NOTUMHTR2C | |
| SCHEMBL30422322 | 0.81 | PARP1 (0.50) | PARP10PARP11PARP1BCHEACHE | |
| SCHEMBL30421478 | 0.81 | PARP10 (0.48) | PARP10PARP11NOTUMHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110128415-B | Indoline compound used as immunomodulator and preparation method thereof | 沈阳药科大学 | 2022-03-25 | — | — | CN | disclosed |