Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 2/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22979915 | 1.00 | KDM4E (0.39) | KDM4EADORA1ADORA2AMKNK1MKNK2 | |
| SCHEMBL22979154 | 0.92 | ADORA2A (0.41) | KDM4EADORA1ADORA2AMKNK1MKNK2 | |
| SCHEMBL29648840 | 0.92 | ADORA2A (0.41) | KDM4EADORA1ADORA2AMKNK1MKNK2 | |
| SCHEMBL29648759 | 0.90 | KDM4E (0.39) | KDM4EADORA1ADORA2AMKNK1MKNK2 | |
| SCHEMBL22979344 | 0.90 | KDM4E (0.39) | KDM4EADORA1ADORA2AMKNK1MKNK2 | |
| SCHEMBL22979322 | 0.90 | KDM4E (0.39) | KDM4EADORA1ADORA2AMKNK1MKNK2 | |
| SCHEMBL31149867 | 0.90 | KDM4E (0.39) | KDM4EADORA1ADORA2AMKNK1MKNK2 | |
| SCHEMBL22979859 | 0.89 | KDM4E (0.38) | KDM4EADORA1ADORA2AMKNK1MKNK2 | |
| SCHEMBL29648627 | 0.89 | KDM4E (0.38) | KDM4EADORA1ADORA2AMKNK1MKNK2 | |
| SCHEMBL22988344 | 0.88 | MAPT (0.34) | KDM4EMAPTPLATCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | claimed |
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | claimed |