Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 11/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 11/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22988432 | 1.00 | ADORA2A (0.33) | ADORA2AADORA1ADORA3ADORA2BKCNH2 | |
| SCHEMBL22988475 | 0.91 | ADORA2A (0.35) | ADORA2AADORA1ADORA3ADORA2BKDM4E | |
| SCHEMBL22979399 | 0.90 | BRD4 (0.39) | ADORA2AADORA1ADORA3ADORA2BKCNH2 | |
| SCHEMBL22980897 | 0.90 | CCNT1 (0.31) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL22988490 | 0.90 | CCNT1 (0.31) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL22979849 | 0.90 | ADORA2A (0.34) | ADORA2AADORA1ADORA3ADORA2BPIM1 | |
| SCHEMBL22978983 | 0.90 | ADORA2A (0.34) | ADORA2AADORA1ADORA3ADORA2BKDM4E | |
| SCHEMBL29648773 | 0.90 | ADORA2A (0.34) | ADORA2AADORA1ADORA3ADORA2BPIM1 | |
| SCHEMBL22979348 | 0.89 | ADORA2A (0.34) | ADORA2AADORA1ADORA3ADORA2BPIM1 | |
| SCHEMBL22988463 | 0.89 | ADORA2A (0.34) | ADORA2AADORA1ADORA3ADORA2BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | claimed |
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | claimed |