Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | C1R | P00736 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 4/20 | 0.33 |
| ▸ | ACP1 | P24666 | 1/20 | 0.33 |
| ▸ | TACR2 | P21452 | 2/20 | 0.33 |
| ▸ | TACR1 | P25103 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22979159 | 1.00 | MKNK1 (0.36) | MKNK1MKNK2DDB1CRBNMAPT | |
| SCHEMBL29648649 | 0.95 | MAPT (0.36) | MKNK1MKNK2DDB1CRBNMAPT | |
| SCHEMBL29648841 | 0.95 | MAPT (0.36) | MKNK1MKNK2DDB1CRBNMAPT | |
| SCHEMBL22981140 | 0.95 | MAPT (0.36) | MKNK1MKNK2DDB1CRBNMAPT | |
| SCHEMBL22979040 | 0.95 | MAPT (0.36) | MKNK1MKNK2DDB1CRBNMAPT | |
| SCHEMBL22987931 | 0.93 | MKNK1 (0.39) | MKNK1MKNK2DDB1CRBNMAPT | |
| SCHEMBL22979222 | 0.93 | MKNK1 (0.39) | MKNK1MKNK2DDB1CRBNMAPT | |
| SCHEMBL29648829 | 0.93 | MKNK1 (0.39) | MKNK1MKNK2DDB1CRBNMAPT | |
| SCHEMBL29648695 | 0.93 | MKNK1 (0.39) | MKNK1MKNK2DDB1CRBNMAPT | |
| SCHEMBL22988023 | 0.92 | MKNK1 (0.38) | MKNK1MKNK2DDB1CRBNMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | claimed |