Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.38 |
| ▸ | SYK | P43405 | 3/20 | 0.38 |
| ▸ | ZAP70 | P43403 | 2/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29648574 | 1.00 | KDM4E (0.44) | KDM4EALDH1A1POLBXDHTNKS | |
| SCHEMBL22979245 | 1.00 | KDM4E (0.44) | KDM4EALDH1A1POLBXDHTNKS | |
| SCHEMBL22979943 | 1.00 | KDM4E (0.44) | KDM4EALDH1A1POLBXDHTNKS | |
| SCHEMBL29648728 | 0.92 | SYK (0.46) | KDM4EALDH1A1ADORA1ADORA2AMAPT | |
| SCHEMBL29648635 | 0.92 | SYK (0.46) | KDM4EALDH1A1ADORA1ADORA2AMAPT | |
| SCHEMBL22979962 | 0.92 | SYK (0.46) | KDM4EALDH1A1ADORA1ADORA2AMAPT | |
| SCHEMBL22979510 | 0.92 | SYK (0.46) | KDM4EALDH1A1ADORA1ADORA2AMAPT | |
| SCHEMBL22988243 | 0.92 | KDM4E (0.44) | KDM4EALDH1A1POLBXDHTNKS | |
| SCHEMBL22981055 | 0.91 | KDM4E (0.43) | KDM4EALDH1A1POLBXDHADORA1 | |
| SCHEMBL22979371 | 0.91 | KDM4E (0.43) | KDM4EALDH1A1POLBXDHADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | claimed |
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | claimed |