Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4EBP1 | Q13541 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22866435 | 1.00 | EIF4EBP1 (1.00) | EIF4EBP1 | |
| SCHEMBL29650474 | 0.97 | EIF4EBP1 (1.00) | EIF4EBP1 | |
| SCHEMBL29650413 | 0.97 | EIF4EBP1 (1.00) | EIF4EBP1 | |
| SCHEMBL29650580 | 0.95 | EIF4EBP1 (0.93) | EIF4EBP1 | |
| SCHEMBL29650479 | 0.95 | EIF4EBP1 (1.00) | EIF4EBP1 | |
| SCHEMBL29650494 | 0.94 | EIF4EBP1 (1.00) | EIF4EBP1 | |
| SCHEMBL29468134 | 0.94 | EIF4EBP1 (0.91) | EIF4EBP1 | |
| SCHEMBL22866443 | 0.94 | EIF4EBP1 (0.91) | EIF4EBP1 | |
| SCHEMBL29650492 | 0.94 | EIF4EBP1 (1.00) | EIF4EBP1 | |
| SCHEMBL29650421 | 0.92 | EIF4EBP1 (1.00) | EIF4EBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3994139-A1 | EIF4E-INHIBITING 4-OXO-3,4-DIHYDROPYRIDO[3,4-D]PYRIMIDINE COMPOUNDS | Effector Therapeutics Inc. (US) | 2022-05-11 | — | — | EP | disclosed |
| EP-3993875-A1 | METHODS OF TREATING BRAF-MUTATED CANCER CELLS | EFFECTOR THERAPEUTICS, INC. (US) | 2022-05-11 | — | — | EP | disclosed |