Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.54 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 2/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29650569 | 0.88 | GRIN2B (0.53) | GRIN2BGRIN2CTSHRJAK3 | |
| SCHEMBL17351873 | 0.78 | GRIN2B (0.61) | GRIN2BGRIN2CTSHRJAK3 | |
| SCHEMBL17359174 | 0.78 | GRIN2B (0.61) | GRIN2BGRIN2CTSHRJAK3 | |
| SCHEMBL19134413 | 0.78 | GRIN2B (0.61) | GRIN2BGRIN2CTSHRJAK3 | |
| SCHEMBL15937148 | 0.78 | GRIN2B (0.59) | GRIN2BGRIN2CJAK3 | |
| SCHEMBL15937196 | 0.75 | GRIN2B (0.53) | GRIN2BGRIN2CJAK3 | |
| SCHEMBL15937072 | 0.74 | GRIN2B (0.55) | GRIN2BGRIN2CJAK3 | |
| SCHEMBL20126632 | 0.73 | GRIN2B (0.56) | GRIN2BGRIN2CTSHRJAK3 | |
| SCHEMBL21466075 | 0.73 | GRIN2B (0.63) | GRIN2BGRIN2CJAK3 | |
| SCHEMBL15937080 | 0.72 | GRIN2B (0.52) | GRIN2BGRIN2CJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109661398-B | Spiro-lactam and di-spiro-lactam NMDA receptor modulators and uses thereof | 阿普廷伊克斯股份有限公司 | 2022-07-05 | — | — | CN | disclosed |