Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30843879 | 0.87 | CYP1A2 (0.62) | MAPTCYP1A2CYP3A4CLK4ALDH1A1 | |
| SCHEMBL13272569 | 0.87 | CYP1A2 (0.62) | MAPTCYP1A2CYP3A4CLK4ALDH1A1 | |
| SCHEMBL30804557 | 0.87 | CYP1A2 (0.62) | MAPTCYP1A2CYP3A4CLK4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11861199 | 0.86 | CYP1A2 (0.61) | MAPTCYP1A2CYP3A4CLK4ALDH1A1 | |
| SCHEMBL21875480 | 0.85 | LATS1 (0.61) | LATS1LATS2 | |
| SCHEMBL6090261 | 0.81 | ADORA2A (0.44) | MAPTADORA2AADORA1CYP1A2CYP3A4 | |
| SCHEMBL14727632 | 0.81 | CYP1A2 (0.50) | MAPTADORA2AADORA1CYP1A2CYP3A4 | |
| SCHEMBL29859473 | 0.79 | SMN1; SMN2 (0.57) | MAPTADORA2AADORA1CYP1A2CYP3A4 | |
| SCHEMBL2154726 | 0.78 | KMT2A (0.55) | MAPTADORA2AADORA1CYP1A2CYP3A4 | |
| SCHEMBL20273560 | 0.78 | ADORA2A (0.49) | MAPTADORA2AADORA1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114703144-A | 6-6 fused bicyclic heteroaryl compounds and their use as LATS inhibitors | 诺华股份有限公司 | 2022-07-05 | — | — | CN | disclosed |
| CN-114621222-A | 6-6 fused bicyclic heteroaryl compounds and their use as LATS inhibitors | 诺华股份有限公司 | 2022-06-14 | — | — | CN | disclosed |