Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.53 |
| ▸ | PI4KA | P42356 | 3/20 | 0.53 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.53 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.53 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.53 |
| ▸ | PIK3CD | O00329 | 7/20 | 0.46 |
| ▸ | EGFR | P00533 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | TEK | Q02763 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8577 | 1.00 | ADORA2A (0.53) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL8166 | 0.93 | ADORA2A (0.47) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL30670890 | 0.93 | ADORA2A (0.47) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL11901826 | 0.92 | ADORA2A (0.57) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL30013159 | 0.90 | ADORA2A (0.49) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL8903 | 0.90 | ADORA2A (0.49) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL15688607 | 0.90 | ADORA2A (0.55) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL8426 | 0.90 | PIK3CD (0.46) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL30013691 | 0.90 | PIK3CD (0.46) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL7930 | 0.89 | ADORA2A (0.48) | ADORA2API4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117222413-A | Methods and combinations for treating tumors | 同润生物医药(上海)有限公司 | 2023-12-12 | — | — | CN | claimed |
| CN-117222413-A | Methods and combinations for treating tumors | 同润生物医药(上海)有限公司 | 2023-12-12 | — | — | CN | disclosed |
| EP-2916868-B1 | PHARMACEUTICAL COMPOSITIONS CONTAINING A PDE4 INHIBITOR AND A PI3 DELTA OR DUAL PI3 DELTA-GAMMA KINASE INHIBITOR | RHIZEN PHARMACEUTICALS S A (CH) | 2022-05-11 | — | — | EP | disclosed |