SCHEMBL29654635 — predicted protein targets

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	SMYD2	Q9NRG4	3/20	0.35

▸	CYP3A4	P08684	1/20	0.33

▸	HTT	P42858	1/20	0.33

▸	SMN1; SMN2	Q16637	1/20	0.33

▸	ABL1	P00519	1/20	0.32

▸	NR1H2	P55055	1/20	0.31

▸	NR1H3	Q13133	1/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29654597	0.87	SMYD2 (0.33)	SMYD2CYP3A4HTTSMN1; SMN2
SCHEMBL2912786	0.85	SMYD2 (0.38)	SMYD2CYP3A4HTTSMN1; SMN2ABL1
SCHEMBL4130523	0.82	SMYD2 (0.36)	SMYD2CYP3A4HTTSMN1; SMN2ABL1
SCHEMBL19689304	0.82	SMYD2 (0.36)	SMYD2CYP3A4HTTSMN1; SMN2ABL1
SCHEMBL4132970	0.82	SMYD2 (0.36)	SMYD2CYP3A4HTTSMN1; SMN2ABL1
SCHEMBL29654714	0.82	SMYD2 (0.33)	SMYD2CYP3A4HTTSMN1; SMN2ABL1
SCHEMBL13596143	0.81	SMYD2 (0.36)	SMYD2CYP3A4HTTSMN1; SMN2ABL1
SCHEMBL15016366	0.81	SMYD2 (0.38)	SMYD2CYP3A4HTTSMN1; SMN2NR1H2
SCHEMBL21694640	0.79	SMYD2 (0.39)	SMYD2CYP3A4HTTSMN1; SMN2NR1H2
SCHEMBL4130620	0.79	SMYD2 (0.33)	SMYD2CYP3A4HTTSMN1; SMN2ABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2022133345-A1	TRICYCLIC PYRIDONES AND PYRIMIDONES	ERASCA, INC. (US)	2022-06-23	—	—	WO	disclosed