Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24525573 | 1.00 | AR (0.38) | ARPOLBHTTMEN1KMT2A | |
| SCHEMBL29654372 | 0.81 | CYP3A4 (0.40) | ARPOLBHTTMEN1KMT2A | |
| SCHEMBL24525255 | 0.81 | CYP3A4 (0.40) | ARPOLBHTTMEN1KMT2A | |
| SCHEMBL31118684 | 0.68 | MEN1 (0.43) | ARMEN1KMT2AALPLALDH1A1 | |
| SCHEMBL29604734 | 0.68 | AR (0.47) | ARPOLBHTTMEN1KMT2A | |
| SCHEMBL21988948 | 0.66 | PIM3 (0.37) | ARPOLBALPLALDH1A1FFAR4 | |
| SCHEMBL23287467 | 0.65 | — | — | |
| SCHEMBL20243060 | 0.65 | HTT (0.40) | HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL1631298 | 0.65 | KMT2A (0.45) | ARHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL6683354 | 0.65 | MEN1 (0.46) | POLBHTTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025125665-A1 | FURTHER SUBSTITUTED IMIDAZOLES AS INHIBITORS OF NAV1.8 | Grünenthal GmbH (DE) | 2025-06-19 | — | — | WO | disclosed |
| WO-2022133345-A1 | TRICYCLIC PYRIDONES AND PYRIMIDONES | ERASCA, INC. (US) | 2022-06-23 | — | — | WO | disclosed |