Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 16/20 | 0.68 |
| ▸ | PARP1 | P09874 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19748630 | 1.00 | AR (0.68) | ARPARP1LMNAHTTNPSR1 | |
| SCHEMBL12955359 | 0.81 | AR (1.00) | ARPARP1LMNAHTTNPSR1 | |
| SCHEMBL29655150 | 0.81 | AR (0.68) | ARPARP1LMNAHTTNPSR1 | |
| SCHEMBL19748393 | 0.81 | AR (0.68) | ARPARP1LMNAHTTNPSR1 | |
| SCHEMBL29655013 | 0.81 | AR (0.67) | ARPARP1LMNAHTTNPSR1 | |
| SCHEMBL19748608 | 0.81 | AR (0.67) | ARPARP1LMNAHTTNPSR1 | |
| SCHEMBL12955377 | 0.79 | AR (0.68) | ARPARP1LMNAHTTNPSR1 | |
| SCHEMBL29655109 | 0.77 | AR (0.71) | ARPARP1LMNAHTTNPSR1 | |
| SCHEMBL19747503 | 0.77 | AR (0.71) | ARPARP1LMNAHTTNPSR1 | |
| SCHEMBL19748563 | 0.76 | ENPP1 (0.64) | ARPARP1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109843874-B | Phthalazine derivatives useful as inhibitors of PARP1, PARP2 and/or tubulin for the treatment of cancer | 加利福尼亚大学董事会 | 2022-05-27 | — | — | CN | disclosed |