SCHEMBL29655640

SCHEMBL29655640

CC(=O)c1c(C)cc(O)cc1O

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 8/20 0.74
MEN1 O00255 4/20 0.74
KMT2A Q03164 4/20 0.74
HPGD P15428 3/20 0.74
ACHE P22303 2/20 0.69
SMN1; SMN2 Q16637 3/20 0.58
TDP1 Q9NUW8 1/20 0.58
POLB P06746 1/20 0.53
MAPK1 P28482 3/20 0.51
LMNA P02545 2/20 0.51
ALDH1A1 P00352 1/20 0.51
ALOX15 P16050 1/20 0.51
HSD17B10 Q99714 1/20 0.51
NR1H2 P55055 1/20 0.48
NR1H3 Q13133 1/20 0.48
PTGS1 P23219 1/20 0.48
DRD3 P35462 1/20 0.48
FASN P49327 1/20 0.46
NPSR1 Q6W5P4 2/20 0.46
USP2 O75604 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3279944 1.00 CYP3A4 (0.74) CYP3A4MEN1KMT2AHPGDACHE
SCHEMBL2380154 0.88 CYP3A4 (0.61) CYP3A4MEN1KMT2AHPGDACHE
2,4,6-Trihydroxyacetophenone SCHEMBL105416 0.85 CYP3A4 (1.00) CYP3A4MEN1KMT2AHPGDACHE
SCHEMBL7766611 0.84 CYP3A4 (0.72) CYP3A4MEN1KMT2AHPGDACHE
2,4,6-Trihydroxyacetophenone SCHEMBL564755 0.83 CYP3A4 (0.95) CYP3A4MEN1KMT2AHPGDACHE
2,4,6-Trihydroxyacetophenone SCHEMBL1421619 0.83 CYP3A4 (0.95) CYP3A4MEN1KMT2AHPGDACHE
SCHEMBL2648126 0.82 CYP3A4 (0.54) CYP3A4MEN1KMT2AHPGDACHE
Orsellinic Acid SCHEMBL522294 0.82 CYP3A4 (1.00) CYP3A4MEN1KMT2AHPGDACHE
SCHEMBL30597490 0.82 CYP3A4 (0.54) CYP3A4MEN1KMT2AHPGDACHE
SCHEMBL31738485 0.80 CYP3A4 (0.67) CYP3A4MEN1KMT2AHPGDACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118619911-A Racemized dihydro Synthesis method of quercetin 湖南康和霖生物技术有限公司 2024-09-10 CN claimed
EP-4683918-A1 NLRP3 INFLAMMASOME INHIBITORS AND USES THEREOF Insilico Medicine IP Limited (HK) 2026-01-28 EP disclosed
CN-118804939-A Modified phenolic resins for use in the manufacture of composite products 巴克莱特英国控股有限公司 2024-10-18 CN disclosed
WO-2024193541-A1 NLRP3 INFLAMMASOME INHIBITORS AND USES THEREOF INSILICO MEDICINE IP LIMITED (CN) 2024-09-26 WO disclosed
CN-118619911-A Racemized dihydro Synthesis method of quercetin 湖南康和霖生物技术有限公司 2024-09-10 CN disclosed
CN-111286495-B Aloe C-glycosyltransferase sequence and application thereof in catalyzing C-glycosylation 中国医学科学院药物研究所 2022-05-20 CN disclosed