Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | ACP1 | P24666 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6467338 | 1.00 | NOTUM (0.51) | NOTUMIDO1ACP1SIGMAR1HTR2A | |
| SCHEMBL26074528 | 0.84 | IDO1 (0.46) | NOTUMIDO1SIGMAR1HTR2AHTR2B | |
| SCHEMBL148275 | 0.84 | IDO1 (0.52) | NOTUMIDO1SIGMAR1HTR2AHTR2B | |
| SCHEMBL9886099 | 0.84 | NOTUM (0.45) | NOTUMIDO1ACP1SIGMAR1HTR2A | |
| SCHEMBL3591051 | 0.81 | IDO1 (0.41) | NOTUMIDO1ACP1HTR2AHTR2B | |
| SCHEMBL14228534 | 0.81 | HSPA5 (0.36) | NOTUMIDO1LMNA | |
| SCHEMBL29738521 | 0.81 | IDO1 (0.41) | NOTUMIDO1ACP1HTR2AHTR2B | |
| SCHEMBL9885347 | 0.80 | NOTUM (0.41) | NOTUMIDO1ACP1HTR2AHTR2B | |
| SCHEMBL16727009 | 0.80 | IDO1 (0.46) | NOTUMIDO1ACP1SLC6A4TACR1 | |
| SCHEMBL25368340 | 0.79 | NOTUM (0.40) | NOTUMIDO1ACP1DDR1S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114761383-A | Sulfonamide derivatives and uses thereof | 诺瑟拉有限公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-114539245-A | Pyrimidine-fused ring derivative-containing regulator, and preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2022-05-27 | — | — | CN | disclosed |