Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 2/20 | 0.69 |
| ▸ | FGFR1 | P11362 | 18/20 | 0.54 |
| ▸ | FLT1 | P17948 | 4/20 | 0.54 |
| ▸ | PDGFRB | P09619 | 15/20 | 0.50 |
| ▸ | KDR | P35968 | 15/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.50 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29656957 | 0.89 | LCK (0.55) | LCKFGFR1FLT1PDGFRBKDR | |
| SCHEMBL29656917 | 0.88 | LCK (0.54) | LCKFGFR1FLT1PDGFRBKDR | |
| SCHEMBL28734078 | 0.85 | LCK (0.52) | LCKFGFR1FLT1PDGFRBKDR | |
| SCHEMBL25778573 | 0.84 | LCK (0.61) | LCKFGFR1FLT1PDGFRBKDR | |
| SCHEMBL3381734 | 0.83 | FGFR1 (0.74) | FGFR1FLT1PDGFRBKDR | |
| SCHEMBL20293443 | 0.82 | LCK (1.00) | LCKFGFR1FLT1PDGFRBKDR | |
| SCHEMBL29656942 | 0.81 | LCK (0.51) | LCKFGFR1FLT1PDGFRBKDR | |
| SCHEMBL20293394 | 0.80 | LCK (0.66) | LCKFGFR1FLT1PDGFRBKDR | |
| SCHEMBL26081348 | 0.80 | LCK (0.86) | LCKFGFR1FLT1PDGFRBKDR | |
| SCHEMBL29656935 | 0.79 | LCK (0.47) | LCKFGFR1FLT1PDGFRBKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109721620-B | HPK1 inhibitors and uses thereof | 药捷安康(南京)科技股份有限公司 | 2022-05-13 | — | — | CN | disclosed |