SCHEMBL29657239

SCHEMBL29657239

O=C(O)c1cc(S(=O)(=O)O)c2cc(C(=O)O)cc(S(=O)(=O)O)c2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.56
FYN P06241 1/20 0.56
CDC25B P30305 1/20 0.42
CA12 O43570 2/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA7 P43166 2/20 0.41
CA9 Q16790 2/20 0.41
CA14 Q9ULX7 2/20 0.41
TDP1 Q9NUW8 3/20 0.40
ALDH1A1 P00352 2/20 0.40
HSD17B10 Q99714 2/20 0.40
CASP1 P29466 1/20 0.40
CASP7 P55210 1/20 0.40
CYP1A2 P05177 1/20 0.39
TPMT P51580 3/20 0.39
TP53 P04637 2/20 0.39
KDM4E B2RXH2 1/20 0.39
LMNA P02545 1/20 0.39
CA3 P07451 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3841219 1.00 LCK (0.56) LCKFYNCDC25BCA12CA1
SCHEMBL1602834 0.98 LCK (0.54) LCKFYNCDC25BCA12CA1
SCHEMBL25201100 0.87 TTR (0.51) LCKFYNCDC25BCYP1A2TSHR
SCHEMBL29763597 0.85 CDC25B (0.47) LCKFYNCDC25BTDP1ALDH1A1
SCHEMBL976104 0.85 CDC25B (0.47) LCKFYNCDC25BTDP1ALDH1A1
SCHEMBL1602218 0.83 CDC25B (0.46) LCKFYNCDC25BTDP1ALDH1A1
SCHEMBL7939204 0.83 CDC25B (0.46) LCKFYNCDC25BTDP1ALDH1A1
SCHEMBL7941298 0.83 CDC25B (0.46) LCKFYNCDC25BTDP1ALDH1A1
SCHEMBL9178407 0.83 CDC25B (0.46) LCKFYNCDC25BTDP1ALDH1A1
SCHEMBL29365363 0.81 PTPN1 (0.50) LCKFYNCDC25BCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12416046-B2 Labeled nucleotide analogs, reaction mixtures, and methods and systems for sequencing PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2025-09-16 US disclosed
US-12391834-B2 Protected dye-labeled reagents PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2025-08-19 US disclosed
US-20250188534-A1 MODIFIED NUCLEOTIDE REAGENTS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2025-06-12 US disclosed
US-20250002989-A1 LABELED NUCLEOTIDE ANALOGS, REACTION MIXTURES, AND METHODS AND SYSTEMS FOR SEQUENCING PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2025-01-02 US disclosed
EP-3376997-B1 LABELED NUCLEOTIDE ANALOGS, REACTION MIXTURES, AND METHODS AND SYSTEMS FOR SEQUENCING PACIFIC BIOSCIENCES CALIFORNIA INC (US) 2024-11-13 EP disclosed
US-12037641-B2 Modified nucleotide reagents PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2024-07-16 US disclosed
US-12000000-B2 Labeled nucleotide analogs, reaction mixtures, and methods and systems for sequencing PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2024-06-04 US disclosed
US-20240158640-A1 PROTECTED DYE-LABELED REAGENTS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2024-05-16 US disclosed
US-20240052410-A1 MODIFIED NUCLEOTIDE REAGENTS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2024-02-15 US disclosed
US-11884826-B2 Protected dye-labeled reagents PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2024-01-30 US disclosed
US-20230366018-A1 LABELED NUCLEOTIDE ANALOGS, REACTION MIXTURES, AND METHODS AND SYSTEMS FOR SEQUENCING PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2023-11-16 US disclosed
EP-4219506-A1 PROTECTED DYE-LABELED REAGENTS Pacific Biosciences Of California, Inc. (US) 2023-08-02 EP disclosed
US-20220396702-A1 PROTECTED DYE-LABELED REAGENTS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2022-12-15 US disclosed
US-11466319-B2 Labeled nucleotide analogs, reaction mixtures, and methods and systems for sequencing PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2022-10-11 US disclosed
EP-3376996-B1 PROTECTED DYE-LABELED REAGENTS PACIFIC BIOSCIENCES CALIFORNIA INC (US) 2022-09-07 EP disclosed
US-11359235-B2 Modified nucleotide reagents PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2022-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11359235-B2 Modified nucleotide reagents POLL, POLN, POLM LCK 4784/4885FYN 4853/4885CDC25B 2187/4885
US-20250002989-A1 LABELED NUCLEOTIDE ANALOGS, REACTION MIXTURES, AND METHODS AND SYSTEMS FOR SEQUENCING POLL, POLN, POLB LCK 4785/4885FYN 4840/4885CDC25B 2783/4885
US-12391834-B2 Protected dye-labeled reagents POLL, POLB, POLM LCK 4815/4885FYN 4857/4885CDC25B 2629/4885
US-11884826-B2 Protected dye-labeled reagents POLL, POLB, POLM LCK 4815/4885FYN 4857/4885CDC25B 2629/4885
US-12037641-B2 Modified nucleotide reagents POLL, POLN, POLM LCK 4784/4885FYN 4853/4885CDC25B 2187/4885
US-20220396702-A1 PROTECTED DYE-LABELED REAGENTS POLL, POLB, POLM LCK 4815/4885FYN 4857/4885CDC25B 2629/4885
US-20250188534-A1 MODIFIED NUCLEOTIDE REAGENTS POLL, POLN, POLM LCK 4784/4885FYN 4853/4885CDC25B 2187/4885
US-12416046-B2 Labeled nucleotide analogs, reaction mixtures, and methods and systems for sequencing POLL, POLN, POLB LCK 4785/4885FYN 4840/4885CDC25B 2783/4885
US-12000000-B2 Labeled nucleotide analogs, reaction mixtures, and methods and systems for sequencing POLL, POLN, POLB LCK 4785/4885FYN 4840/4885CDC25B 2783/4885
US-20240052410-A1 MODIFIED NUCLEOTIDE REAGENTS POLL, POLN, POLM LCK 4784/4885FYN 4853/4885CDC25B 2187/4885
US-11466319-B2 Labeled nucleotide analogs, reaction mixtures, and methods and systems for sequencing POLL, POLN, POLB LCK 4785/4885FYN 4840/4885CDC25B 2783/4885
US-20230366018-A1 LABELED NUCLEOTIDE ANALOGS, REACTION MIXTURES, AND METHODS AND SYSTEMS FOR SEQUENCING POLL, POLN, POLB LCK 4785/4885FYN 4840/4885CDC25B 2783/4885
US-20240158640-A1 PROTECTED DYE-LABELED REAGENTS POLL, POLB, POLM LCK 4815/4885FYN 4857/4885CDC25B 2629/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.