Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 20/20 | 0.61 |
| ▸ | BCL2L1 | Q07817 | 5/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2724654 | 1.00 | BCL2 (0.61) | BCL2BCL2L1 | |
| SCHEMBL2725866 | 0.92 | BCL2 (0.61) | BCL2BCL2L1 | |
| SCHEMBL29657285 | 0.92 | BCL2 (0.61) | BCL2BCL2L1 | |
| SCHEMBL30314189 | 0.88 | BCL2 (0.56) | BCL2BCL2L1 | |
| SCHEMBL30313851 | 0.87 | BCL2 (0.63) | BCL2BCL2L1 | |
| SCHEMBL30314012 | 0.87 | BCL2 (0.63) | BCL2BCL2L1 | |
| SCHEMBL29657441 | 0.84 | BCL2 (0.60) | BCL2BCL2L1 | |
| SCHEMBL2724019 | 0.84 | BCL2 (0.60) | BCL2BCL2L1 | |
| SCHEMBL29657360 | 0.83 | BCL2 (0.59) | BCL2BCL2L1 | |
| SCHEMBL1873478 | 0.83 | BCL2 (0.59) | BCL2BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4243857-A1 | COMBINATION THERAPIES WITH CHIMERIC ANTIGEN RECEPTOR (CAR)-EXPRESSING CELLS | Novartis AG (CH) | 2023-09-20 | — | — | EP | disclosed |
| CN-116635062-A | Combination therapy using Chimeric Antigen Receptor (CAR) expressing cells | 诺华股份有限公司 | 2023-08-22 | — | — | CN | disclosed |
| WO-2022104061-A1 | COMBINATION THERAPIES WITH CHIMERIC ANTIGEN RECEPTOR (CAR)-EXPRESSING CELLS | NOVARTIS AG (CH) | 2022-05-19 | — | — | WO | disclosed |