Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 7/20 | 0.50 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1580896 | 0.96 | F2R (0.46) | F2RCCR2EPHX2HCRTR2ESR1 | |
| SCHEMBL1580743 | 0.92 | F2R (0.40) | F2RCCR2HCRTR2ESR1ESR2 | |
| SCHEMBL27797979 | 0.91 | F2R (0.49) | F2RCCR2EPHX2HCRTR2DRD2 | |
| SCHEMBL1581262 | 0.90 | F2R (0.51) | F2RCCR2EPHX2HCRTR2ESR1 | |
| SCHEMBL1580972 | 0.90 | F2R (0.52) | F2REPHX2DRD2CHRM4GRIN2B | |
| SCHEMBL1580858 | 0.89 | F2R (0.50) | F2RCCR2GRIN2BKIF11 | |
| SCHEMBL27798015 | 0.88 | F2R (0.44) | F2RCCR2EPHX2HCRTR2ESR1 | |
| SCHEMBL1581140 | 0.87 | F2R (0.43) | F2RHCRTR2 | |
| SCHEMBL1580784 | 0.87 | F2R (0.47) | F2RCCR2EPHX2HCRTR2DRD2 | |
| SCHEMBL641859 | 0.86 | F2R (0.53) | F2RCCR2EPHX2HCRTR2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2227466-A2 | HETEROARYL-SUBSTITUTED PIPERIDINES | Bayer Schering Pharma Aktiengesellschaft (DE) | 2010-09-15 | — | — | EP | disclosed |
| WO-2009068214-A2 | HETEROARYL-SUBSTITUTED PIPERIDINES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-06-04 | — | — | WO | disclosed |