Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.58 |
| ▸ | ECE1 | P42892 | 9/20 | 0.54 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.54 |
| ▸ | MAGI3 | Q5TCQ9 | 1/20 | 0.53 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31222656 | 0.91 | ACE (0.63) | ACEECE1 | |
| SCHEMBL31299590 | 0.89 | IL23R (0.58) | ACEIL23RERBB2 | |
| SCHEMBL30724706 | 0.88 | ACE (0.62) | ACEECE1 | |
| SCHEMBL31039961 | 0.87 | MAGI3 (0.58) | ACEECE1MAGI3ERBB2 | |
| SCHEMBL32667969 | 0.87 | ERAP2 (0.60) | ECE1 | |
| SCHEMBL29851151 | 0.86 | ACE (0.57) | ACEECE1MAGI3 | |
| SCHEMBL30604605 | 0.86 | ACE (0.70) | ACEECE1 | |
| SCHEMBL31299579 | 0.86 | ERBB2 (0.58) | ACEECE1IL23RMAGI3ERBB2 | |
| SCHEMBL11689314 | 0.85 | IL23R (0.59) | IL23R | |
| SCHEMBL11691996 | 0.85 | IL23R (0.59) | IL23R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478789-A | anti-PD-L1 and OX40 bispecific antibodies and uses thereof | 安徽安科生物工程（集团）股份有限公司 | 2022-05-13 | — | — | CN | disclosed |