SCHEMBL29658199

SCHEMBL29658199

O=Cc1cccc(-c2nccs2)c1O

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 5/20 0.44
CYP2A6 P11509 2/20 0.40
PDPK1 O15530 1/20 0.40
TLR2 O60603 1/20 0.39
TLR1 Q15399 1/20 0.39
TLR6 Q9Y2C9 1/20 0.39
ADORA2A P29274 1/20 0.39
ADORA1 P30542 1/20 0.39
CASP6 P55212 1/20 0.36
RAB9A P51151 1/20 0.36
LOXL2 Q9Y4K0 1/20 0.36
HTR2B P41595 1/20 0.36
SMPD3 Q9NY59 1/20 0.36
TRIM24 O15164 2/20 0.35
TRIM33 Q9UPN9 2/20 0.35
HSP90AA1 P07900 1/20 0.35
ADRA1D P25100 1/20 0.34
ADRA1A P35348 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23093262 1.00 ERN1 (0.44) ERN1CYP2A6PDPK1TLR2TLR1
SCHEMBL610449 0.83 PDPK1 (0.48) CYP2A6PDPK1ADORA2AADORA1RAB9A
Hydrochloric Acid SCHEMBL19894001 0.82 PDPK1 (0.47) CYP2A6PDPK1ADORA2AADORA1RAB9A
SCHEMBL1954807 0.78 PDPK1 (0.46) CYP2A6PDPK1ADORA2AADORA1CASP6
SCHEMBL23108267 0.78 CA1 (0.46) ERN1CYP2A6PDPK1TLR2TLR1
SCHEMBL29833478 0.76 ERN1 (0.51) ERN1SMPD3HSP90AA1
SCHEMBL23249815 0.76 ADORA2A (0.48) CYP2A6PDPK1ADORA2AADORA1CASP6
SCHEMBL16439936 0.75 ERN1 (0.67) ERN1TLR2TLR1TLR6TRIM24
SCHEMBL31152506 0.75 ERN1 (0.67) ERN1TLR2TLR1TLR6TRIM24
SCHEMBL23092920 0.74 HTR2B (0.44) ERN1CYP2A6TLR2TLR1TLR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114478514-B Fluorescent molecular probe with aggregation-induced emission characteristic and preparation method and application thereof 湖南省肿瘤医院 2023-04-18 CN claimed
CN-114478514-A Fluorescent molecular probe with aggregation-induced emission characteristic and preparation method and application thereof 湖南省肿瘤医院 2022-05-13 CN claimed
CN-114478514-B Fluorescent molecular probe with aggregation-induced emission characteristic and preparation method and application thereof 湖南省肿瘤医院 2023-04-18 CN disclosed
CN-114478514-B Fluorescent molecular probe with aggregation-induced emission characteristic and preparation method and application thereof 湖南省肿瘤医院 2023-04-18 CN disclosed
CN-114478514-A Fluorescent molecular probe with aggregation-induced emission characteristic and preparation method and application thereof 湖南省肿瘤医院 2022-05-13 CN disclosed
CN-114478514-A Fluorescent molecular probe with aggregation-induced emission characteristic and preparation method and application thereof 湖南省肿瘤医院 2022-05-13 CN disclosed