Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.74 |
| ▸ | MAPT | P10636 | 5/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.74 |
| ▸ | HPGD | P15428 | 4/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.74 |
| ▸ | POLB | P06746 | 3/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.74 |
| ▸ | LMNA | P02545 | 3/20 | 0.74 |
| ▸ | THPO | P40225 | 3/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.74 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.74 |
| ▸ | BLM | P54132 | 4/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | APEX1 | P27695 | 2/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28760511 | 1.00 | HSD17B10 (0.74) | HSD17B10KDM4EMAPTTDP1HPGD | |
| SCHEMBL28760507 | 1.00 | HSD17B10 (0.74) | HSD17B10KDM4EMAPTTDP1HPGD | |
| SCHEMBL11654746 | 0.86 | HSD17B10 (0.70) | HSD17B10KDM4EMAPTTDP1HPGD | |
| SCHEMBL10728310 | 0.85 | HSD17B10 (0.69) | HSD17B10KDM4EMAPTTDP1HPGD | |
| Carbidopa Anhydrous SCHEMBL30803536 | 0.85 | HSD17B10 (1.00) | HSD17B10KDM4EMAPTTDP1HPGD | |
| Carbidopa Anhydrous SCHEMBL2688295 | 0.85 | HSD17B10 (1.00) | HSD17B10KDM4EMAPTTDP1HPGD | |
| Carbidopa Anhydrous SCHEMBL5051647 | 0.85 | HSD17B10 (1.00) | HSD17B10KDM4EMAPTTDP1HPGD | |
| Carbidopa Anhydrous SCHEMBL29392554 | 0.85 | HSD17B10 (1.00) | HSD17B10KDM4EMAPTTDP1HPGD | |
| Carbidopa Anhydrous SCHEMBL8407333 | 0.85 | HSD17B10 (1.00) | HSD17B10KDM4EMAPTTDP1HPGD | |
| Carbidopa Anhydrous SCHEMBL35084 | 0.85 | HSD17B10 (1.00) | HSD17B10KDM4EMAPTTDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478303-A | Method for synthesizing carbidopa | 浙江野风药业股份有限公司 | 2022-05-13 | — | — | CN | disclosed |