Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | FLT3 | P36888 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CCNE2 | O96020 | 5/20 | 0.52 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.52 |
| ▸ | CDK2 | P24941 | 5/20 | 0.52 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.47 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20547437 | 1.00 | TDP1 (0.66) | TDP1CTSLFLT3NPC1RAB9A | |
| SCHEMBL29659523 | 0.97 | TDP1 (0.68) | TDP1CTSLFLT3NPC1RAB9A | |
| SCHEMBL20547585 | 0.97 | TDP1 (0.68) | TDP1CTSLFLT3NPC1RAB9A | |
| SCHEMBL21954488 | 0.89 | NPC1 (0.66) | TDP1CTSLFLT3NPC1RAB9A | |
| SCHEMBL29659597 | 0.89 | NPC1 (0.66) | TDP1CTSLFLT3NPC1RAB9A | |
| SCHEMBL20547622 | 0.88 | CCNE2 (0.63) | TDP1CTSLFLT3NPC1RAB9A | |
| SCHEMBL30409475 | 0.88 | TDP1 (0.59) | TDP1CTSLFLT3NPC1RAB9A | |
| SCHEMBL21954487 | 0.86 | CCNE2 (0.60) | TDP1CTSLFLT3NPC1RAB9A | |
| SCHEMBL29659588 | 0.86 | CCNE2 (0.60) | TDP1CTSLFLT3NPC1RAB9A | |
| SCHEMBL30410714 | 0.85 | TDP1 (0.61) | TDP1CTSLFLT3NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3615535-B1 | 9-(2-OXACYCLOALKYL)-9H-PURINE-2,6-DIAMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF SKIN DISORDERS | UNIV PALACKEHO (CZ) | 2022-06-15 | — | — | EP | disclosed |