Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 19/20 | 0.63 |
| ▸ | IDH2 | P48735 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23152237 | 1.00 | IDH1 (0.63) | IDH1IDH2 | |
| SCHEMBL23181327 | 0.92 | IDH1 (0.59) | IDH1IDH2 | |
| SCHEMBL29660810 | 0.92 | IDH1 (0.59) | IDH1IDH2 | |
| SCHEMBL29660707 | 0.81 | IDH1 (0.70) | IDH1IDH2 | |
| SCHEMBL29660739 | 0.81 | IDH1 (0.62) | IDH1IDH2 | |
| SCHEMBL23181328 | 0.81 | IDH1 (0.62) | IDH1IDH2 | |
| SCHEMBL23181021 | 0.78 | IDH1 (0.64) | IDH1IDH2 | |
| SCHEMBL23181329 | 0.78 | IDH1 (0.63) | IDH1IDH2 | |
| SCHEMBL29660805 | 0.78 | IDH1 (0.64) | IDH1IDH2 | |
| SCHEMBL23180969 | 0.78 | IDH1 (0.59) | IDH1IDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114502537-A | Mutant IDH2 inhibitor and application thereof | 贝达药业股份有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-114502537-A | Mutant IDH2 inhibitor and application thereof | 贝达药业股份有限公司 | 2022-05-13 | — | — | CN | disclosed |