Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.50 |
| ▸ | HPD | P32754 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
| ▸ | SOD1 | P00441 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23362070 | 1.00 | MAOB (0.50) | MAOBHPDNPC1RAB9AMAPK14 | |
| SCHEMBL19745238 | 0.86 | MAOB (0.51) | MAOBHPDKCNH2 | |
| SCHEMBL27111256 | 0.85 | CHRNB4 (0.43) | MAOBHPDSMPD1KCNH2 | |
| SCHEMBL23286738 | 0.85 | NPC1 (0.40) | MAOBHPDNPC1RAB9AMAPK14 | |
| SCHEMBL30087158 | 0.84 | MAOB (0.48) | MAOBNPC1RAB9ASMPD1SOD1 | |
| SCHEMBL23286263 | 0.84 | MAPK14 (0.41) | MAOBHPDNPC1RAB9AMAPK14 | |
| SCHEMBL27176919 | 0.84 | MAOB (0.48) | MAOBNPC1RAB9ASMPD1SOD1 | |
| SCHEMBL23286794 | 0.82 | MAOB (0.40) | MAOBHPDNPC1RAB9AMAPK14 | |
| SCHEMBL30497335 | 0.82 | PTGER1 (0.47) | MAOBMAPK14 | |
| SCHEMBL23286871 | 0.82 | MAPK14 (0.40) | MAOBHPDNPC1RAB9AMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4373821-A1 | GLUCAGON-LIKE PEPTIDE-1 RECEPTOR MODULATORS AND USES THEREOF | Hepagene Therapeutics (HK) Limited (HK) | 2024-05-29 | — | — | EP | disclosed |
| CN-117715906-A | Glucagon-like peptide-1 receptor modulators and uses thereof | 和博医药有限公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-114728939-B | GLP-1 receptor agonists and uses thereof | 日东制药株式会社 | 2023-12-08 | — | — | CN | disclosed |
| WO-2023001237-A1 | GLUCAGON-LIKE PEPTIDE-1 RECEPTOR MODULATORS AND USES THEREOF | Hepagene Therapeutics (HK) Limited (CN) | 2023-01-26 | — | — | WO | disclosed |
| CN-114728939-A | GLP-1 receptor agonists and uses thereof | 日东制药株式会社 | 2022-07-08 | — | — | CN | disclosed |
| CN-114728940-A | GLP-1 receptor agonists and uses thereof | 日东制药株式会社 | 2022-07-08 | — | — | CN | disclosed |