Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 2/20 | 0.57 |
| ▸ | SKP1 | P63208 | 2/20 | 0.57 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.57 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.55 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.53 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.51 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.51 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.45 |
| ▸ | GBA1 | P04062 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4949224 | 1.00 | CKS1B (0.57) | CKS1BSKP1SKP2MAP4K4GPR119 | |
| SCHEMBL461584 | 0.92 | CKS1B (0.62) | CKS1BSKP1SKP2MAP4K4GPR119 | |
| SCHEMBL461585 | 0.86 | CKS1B (0.60) | CKS1BSKP1SKP2MAP4K4GPR119 | |
| SCHEMBL4524210 | 0.86 | CKS1B (0.57) | CKS1BSKP1SKP2MAP4K4GPR119 | |
| SCHEMBL29574323 | 0.85 | CKS1B (0.56) | CKS1BSKP1SKP2MAP4K4GPR119 | |
| SCHEMBL12633201 | 0.85 | CKS1B (0.59) | CKS1BSKP1SKP2MAP4K4GPR119 | |
| SCHEMBL441495 | 0.85 | CKS1B (0.56) | CKS1BSKP1SKP2MAP4K4GPR119 | |
| SCHEMBL15047026 | 0.85 | CKS1B (0.56) | CKS1BSKP1SKP2MAP4K4GPR119 | |
| SCHEMBL22391574 | 0.85 | CKS1B (0.56) | CKS1BSKP1SKP2MAP4K4GPR119 | |
| SCHEMBL29161592 | 0.85 | CKS1B (0.56) | CKS1BSKP1SKP2MAP4K4GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728939-B | GLP-1 receptor agonists and uses thereof | 日东制药株式会社 | 2023-12-08 | — | — | CN | disclosed |
| CN-114728939-A | GLP-1 receptor agonists and uses thereof | 日东制药株式会社 | 2022-07-08 | — | — | CN | disclosed |