Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.37 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | ACVR2A | P27037 | 1/20 | 0.31 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23215087 | 1.00 | LOX (0.41) | LOXLOXL2SORT1SLC13A5GABRA1 | |
| SCHEMBL23215152 | 0.84 | LOX (0.45) | LOXLOXL2SORT1SLC13A5GABRA1 | |
| SCHEMBL29664692 | 0.84 | LOX (0.45) | LOXLOXL2SORT1SLC13A5GABRA1 | |
| SCHEMBL29664732 | 0.83 | FFAR1 (0.45) | LOXLOXL2SORT1SLC13A5FFAR1 | |
| SCHEMBL23215037 | 0.83 | FFAR1 (0.45) | LOXLOXL2SORT1SLC13A5FFAR1 | |
| SCHEMBL23214882 | 0.82 | LOX (0.38) | LOXLOXL2SORT1SLC13A5GABRA1 | |
| SCHEMBL29664648 | 0.82 | LOX (0.38) | LOXLOXL2SORT1SLC13A5GABRA1 | |
| SCHEMBL23216720 | 0.81 | FFAR1 (0.48) | LOXLOXL2SORT1SLC13A5FFAR1 | |
| SCHEMBL29664623 | 0.81 | FFAR1 (0.48) | LOXLOXL2SORT1SLC13A5FFAR1 | |
| SCHEMBL23216869 | 0.79 | LOX (0.35) | LOXLOXL2SORT1SLC13A5GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114729044-A | Muscarinic acetylcholine M1Receptor antagonists | 帕珀莱恩医疗公司 | 2022-07-08 | — | — | CN | disclosed |