Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL30200144 | 1.00 | — | — | |
| SCHEMBL28855277 | 0.97 | CES1 (0.61) | — | |
| SCHEMBL20284 | 0.97 | — | — | |
| SCHEMBL106748 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL4188396 | 0.94 | — | — | |
| SCHEMBL5829952 | 0.94 | — | — | |
| SCHEMBL29959512 | 0.94 | — | — | |
| SCHEMBL9473171 | 0.94 | — | — | |
| SCHEMBL4135496 | 0.94 | — | — | |
| Iodide SCHEMBL28963599 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555562-A | Solid state forms of (S) -2- (((S) -6, 8-difluoro-1, 2,3, 4-tetrahydronaphthalen-2-yl) amino) -N- (1- (2-methyl-1- (neopentylamino) propan-2-yl) -1H-imidazol-4-yl) pentanamide and uses thereof | 辉瑞公司 | 2022-05-27 | — | — | CN | disclosed |