SCHEMBL29668396

SCHEMBL29668396

O=S(=O)(Nc1cscn1)c1cc(Cl)c(NCc2ccccc2CN2CCC2)cc1F

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SCN8A Q9UQD0 20/20 1.00
SCN1A P35498 19/20 1.00
SCN5A Q14524 19/20 1.00
SCN1B Q07699 3/20 0.84
NR1I2 O75469 1/20 0.84

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20252489 1.00 SCN8A (1.00) SCN8ASCN1ASCN5ASCN1BNR1I2
Trifluoroacetic Acid SCHEMBL20237657 0.94 SCN8A (0.88) SCN8ASCN1ASCN5ASCN1BNR1I2
Trifluoroacetic Acid SCHEMBL29668863 0.94 SCN8A (0.88) SCN8ASCN1ASCN5ASCN1BNR1I2
SCHEMBL20237576 0.93 SCN8A (1.00) SCN8ASCN1ASCN5ASCN1BNR1I2
SCHEMBL29668856 0.93 SCN8A (1.00) SCN8ASCN1ASCN5ASCN1BNR1I2
SCHEMBL29669020 0.92 SCN8A (1.00) SCN8ASCN1ASCN5ASCN1BNR1I2
SCHEMBL20237977 0.92 SCN8A (1.00) SCN8ASCN1ASCN5ASCN1BNR1I2
SCHEMBL20238179 0.92 SCN8A (1.00) SCN8ASCN1ASCN5ASCN1BNR1I2
SCHEMBL20238821 0.92 SCN8A (1.00) SCN8ASCN1ASCN5ASCN1BNR1I2
SCHEMBL29669024 0.92 SCN8A (1.00) SCN8ASCN1ASCN5ASCN1BNR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110325531-B Benzenesulfonamides and their use as therapeutic agents 泽农医药公司 2022-05-27 CN claimed