SCHEMBL29669010

SCHEMBL29669010

O=S(=O)(Nc1cscn1)c1ccc(NCc2c(F)cccc2CN2CCC2)c(Cl)c1F

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SCN8A Q9UQD0 20/20 1.00
SCN1A P35498 18/20 1.00
SCN5A Q14524 18/20 1.00
NR1I2 O75469 1/20 0.78
SCN1B Q07699 1/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20237653 1.00 SCN8A (1.00) SCN8ASCN1ASCN5ANR1I2SCN1B
Formic Acid SCHEMBL20237989 0.96 SCN8A (0.93) SCN8ASCN1ASCN5ANR1I2SCN1B
Formic Acid SCHEMBL29669097 0.96 SCN8A (0.93) SCN8ASCN1ASCN5ANR1I2SCN1B
SCHEMBL20237812 0.91 SCN8A (1.00) SCN8ASCN1ASCN5ANR1I2SCN1B
SCHEMBL29669109 0.88 SCN1A (1.00) SCN8ASCN1ASCN5ANR1I2SCN1B
SCHEMBL22331166 0.88 SCN8A (1.00) SCN8ASCN1ASCN5ANR1I2SCN1B
SCHEMBL30662651 0.88 SCN8A (1.00) SCN8ASCN1ASCN5ANR1I2SCN1B
SCHEMBL20237584 0.88 SCN1A (1.00) SCN8ASCN1ASCN5ANR1I2SCN1B
SCHEMBL29669024 0.88 SCN8A (1.00) SCN8ASCN1ASCN5ANR1I2SCN1B
SCHEMBL20238821 0.88 SCN8A (1.00) SCN8ASCN1ASCN5ANR1I2SCN1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110325531-B Benzenesulfonamides and their use as therapeutic agents 泽农医药公司 2022-05-27 CN disclosed