SCHEMBL29669015

SCHEMBL29669015

O=S(=O)(Nc1ncns1)c1cc(F)c(F)cc1F

nearest known ligand 0.59

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 19/20 0.59
SCN5A Q14524 3/20 0.57
SCN1A P35498 1/20 0.57
SCN8A Q9UQD0 1/20 0.57
SCN2B O60939 1/20 0.54
SCN1B Q07699 1/20 0.54
CYP3A4 P08684 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20238716 1.00 SCN9A (0.59) SCN9ASCN5ASCN1ASCN8ASCN2B
SCHEMBL30479367 0.88 SCN9A (0.55) SCN9ASCN5ASCN1ASCN8ASCN2B
SCHEMBL20449414 0.86 SCN9A (0.55) SCN9ASCN5ASCN1ASCN8ASCN2B
SCHEMBL20449533 0.85 SCN9A (0.54) SCN9ASCN5ASCN1ASCN8ASCN2B
SCHEMBL20449318 0.84 SCN5A (0.54) SCN9ASCN5ASCN1ASCN8ASCN2B
SCHEMBL20449345 0.84 SCN5A (0.52) SCN9ASCN5ASCN1ASCN8ASCN2B
SCHEMBL1095016 0.84 SCN9A (0.56) SCN9ASCN5ASCN1ASCN8A
SCHEMBL29835208 0.84 SCN9A (0.56) SCN9ASCN5ASCN1ASCN8A
SCHEMBL20449412 0.83 SCN5A (0.53) SCN9ASCN5ASCN1ASCN8ASCN2B
SCHEMBL1094279 0.82 SCN9A (0.57) SCN9ASCN5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110325531-B Benzenesulfonamides and their use as therapeutic agents 泽农医药公司 2022-05-27 CN disclosed