Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 20/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 20/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20392592 | 1.00 | ADORA2A (0.57) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL20392690 | 0.91 | ADORA2A (0.56) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL20392609 | 0.89 | ADORA2A (0.60) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL20392552 | 0.88 | ADORA2A (0.56) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL20392541 | 0.85 | ADORA2A (0.60) | ADORA2AADORA1ADORA2B | |
| SCHEMBL20392549 | 0.85 | ADORA2A (0.64) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL20392539 | 0.84 | ADORA2A (0.55) | ADORA2AADORA1ADORA2B | |
| SCHEMBL20667486 | 0.82 | ADORA2A (0.54) | ADORA2AADORA1ADORA3 | |
| SCHEMBL20392680 | 0.81 | ADORA2A (0.53) | ADORA2AADORA1ADORA2B | |
| SCHEMBL20392551 | 0.81 | ADORA2A (0.56) | ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112154144-B | Crystal form of 1,2, 4-triazine-3-amine derivative and preparation method thereof | 江苏恒瑞医药股份有限公司 | 2022-05-27 | — | — | CN | claimed |
| CN-112154144-B | Crystal form of 1,2, 4-triazine-3-amine derivative and preparation method thereof | 江苏恒瑞医药股份有限公司 | 2022-05-27 | — | — | CN | disclosed |