SCHEMBL29670260

CC(C)[C@H](N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	TFPI	P10646	1/20	0.56

▸	BACE1	P56817	3/20	0.50

▸	OPRL1	P41146	5/20	0.49

▸	APC	P25054	1/20	0.48

▸	QRFPR	Q96P65	1/20	0.48

▸	NPY5R	Q15761	3/20	0.47

▸	NPY1R	P25929	2/20	0.47

▸	NPY4R	P50391	2/20	0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29968102	0.89	BACE1 (0.58)	BACE1NPY5RNPY1RNPY4R
SCHEMBL30861237	0.86	QRFPR (0.51)	TFPIQRFPRNPY5RNPY1RNPY4R
SCHEMBL30544262	0.86	FOLH1 (0.53)	TFPIQRFPRNPY5RNPY1RNPY4R
SCHEMBL20764456	0.86	TFPI (0.57)	TFPIBACE1OPRL1
SCHEMBL30818270	0.86	TFPI (0.58)	TFPIOPRL1QRFPR
SCHEMBL30215487	0.85	BACE1 (0.57)	TFPIBACE1NPY5RNPY1RNPY4R
SCHEMBL30512629	0.85	TFPI (0.63)	TFPINPY5RNPY1RNPY4R
SCHEMBL30866942	0.85	NPY4R (0.55)	BACE1NPY5RNPY1RNPY4R
SCHEMBL30184401	0.85	NPY4R (0.53)	TFPINPY5RNPY1RNPY4R
SCHEMBL31064746	0.85	TFPI (0.60)	TFPIBACE1OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-114539387-B	Marine source antifreeze peptide preparation and preparation method and application thereof	浙江万里学院	2023-06-27	—	—	CN	disclosed
CN-114539387-A	Marine-source antifreeze peptide preparation and preparation method and application thereof	浙江万里学院	2022-05-27	—	—	CN	disclosed