Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 13/20 | 0.55 |
| ▸ | EZH2 | Q15910 | 7/20 | 0.55 |
| ▸ | BRD2 | P25440 | 1/20 | 0.55 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.55 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.55 |
| ▸ | EZH1 | Q92800 | 1/20 | 0.55 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.47 |
| ▸ | TAF1 | P21675 | 2/20 | 0.46 |
| ▸ | CECR2 | Q9BXF3 | 2/20 | 0.46 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.46 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.46 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.46 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.46 |
| ▸ | EP300 | Q09472 | 1/20 | 0.46 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.46 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28922767 | 0.92 | BRD4 (0.56) | BRD4EZH2BRD2BRD3BRDT | |
| SCHEMBL29670309 | 0.77 | BRD4 (0.60) | BRD4BRD9TAF1CECR2TRIM24 | |
| SCHEMBL28635044 | 0.76 | BRD4 (0.56) | BRD4EZH2BRD2BRD3BRDT | |
| SCHEMBL29670506 | 0.75 | BRD4 (0.52) | BRD4BRD9TAF1CECR2TRIM24 | |
| SCHEMBL28622612 | 0.74 | BRD4 (0.53) | BRD4BRD9CECR2 | |
| SCHEMBL29670525 | 0.73 | BRD4 (0.51) | BRD4BRD2BRD3BRD9TAF1 | |
| SCHEMBL29670386 | 0.73 | BRD4 (0.62) | BRD4BRD9 | |
| SCHEMBL26331774 | 0.71 | BRD4 (0.70) | BRD4BRD9TAF1CECR2 | |
| SCHEMBL31590651 | 0.71 | BRD4 (0.66) | BRD4BRD9TAF1CECR2TRIM24 | |
| SCHEMBL24866050 | 0.70 | BRD4 (0.76) | BRD4BRD9TAF1CECR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113402515-B | Indole compound and preparation method and application thereof | 四川大学华西医院 | 2022-05-27 | — | — | CN | disclosed |