Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.46 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.46 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.46 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.45 |
| ▸ | FABP3 | P05413 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29497545 | 1.00 | CA1 (0.62) | CA1NFKB1KDM4CKDM4APHF8 | |
| SCHEMBL29670682 | 1.00 | CA1 (0.62) | CA1NFKB1KDM4CKDM4APHF8 | |
| SCHEMBL5666381 | 0.98 | CA1 (0.65) | CA1NFKB1KDM4CKDM4APHF8 | |
| Zinc Ion SCHEMBL28418068 | 0.95 | CA1 (0.62) | CA1NFKB1KDM4CKDM4APHF8 | |
| Potassium Ion SCHEMBL25191979 | 0.95 | CA1 (0.62) | CA1NFKB1KDM4CKDM4APHF8 | |
| SCHEMBL2195531 | 0.95 | CA1 (0.62) | CA1NFKB1KDM4CKDM4APHF8 | |
| SCHEMBL3695162 | 0.95 | CA1 (0.62) | CA1NFKB1KDM4CKDM4APHF8 | |
| SCHEMBL11656700 | 0.95 | CA1 (0.67) | CA1NFKB1KDM4CKDM4APHF8 | |
| SCHEMBL20894203 | 0.95 | CA1 (0.62) | CA1NFKB1KDM4CKDM4APHF8 | |
| SCHEMBL2678684 | 0.95 | CA1 (0.62) | CA1NFKB1KDM4CKDM4APHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11365326-B2 | Thermosetting composition, paint finishing method and method for producing a painted article | AKZO NOBEL COATINGS INTERNATIONAL B.V. | 2022-06-21 | — | — | US | claimed |
| US-11365326-B2 | Thermosetting composition, paint finishing method and method for producing a painted article | AKZO NOBEL COATINGS INTERNATIONAL B.V. | 2022-06-21 | — | — | US | disclosed |