Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | HSD17B13 | Q7Z5P4 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18975047 | 1.00 | KDM4E (0.42) | KDM4EALDH1A1NPC1HSD17B13L3MBTL1 | |
| SCHEMBL15356501 | 0.83 | KDM4E (0.42) | KDM4EALDH1A1NPC1HSD17B13L3MBTL1 | |
| SCHEMBL23146244 | 0.81 | SRC (0.41) | KDM4EALDH1A1NPC1HSD17B13L3MBTL1 | |
| SCHEMBL3436688 | 0.78 | KDM4E (0.48) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1895825 | 0.77 | CYP11B1 (0.56) | KDM4EALDH1A1NPC1RAB9ACYP11B1 | |
| SCHEMBL5539232 | 0.75 | KDM4E (0.42) | KDM4EALDH1A1NPC1HSD17B13RAB9A | |
| SCHEMBL18975046 | 0.74 | PTPN11 (0.43) | KDM4EALDH1A1NPC1RAB9ASRC | |
| SCHEMBL20539648 | 0.73 | HSD17B13 (0.42) | HSD17B13SRCZAP70SYKCYP11B1 | |
| SCHEMBL2095244 | 0.73 | KDM4E (0.46) | KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL2095243 | 0.73 | KDM4E (0.46) | KDM4EALDH1A1NPC1L3MBTL1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114746089-A | Thiazolecarboxamide compounds and their use for the treatment of mycobacterial infections | 结核病药物开发全球联盟公司 | 2022-07-12 | — | — | CN | disclosed |