Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 8/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7843126 | 1.00 | PSEN1 (0.44) | PSEN1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL11440558 | 1.00 | PSEN1 (0.44) | PSEN1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL11440561 | 1.00 | PSEN1 (0.44) | PSEN1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL7056637 | 0.91 | PSEN1 (0.47) | PSEN1MEN1KMT2AMAPTALOX5 | |
| SCHEMBL11446495 | 0.91 | PSEN1 (0.47) | PSEN1MEN1KMT2AMAPTALOX5 | |
| SCHEMBL11446496 | 0.91 | PSEN1 (0.47) | PSEN1MEN1KMT2AMAPTALOX5 | |
| Methane SCHEMBL11453288 | 0.90 | PSEN1 (0.46) | PSEN1MEN1KMT2AMAPTALOX5 | |
| Methane SCHEMBL11453290 | 0.90 | PSEN1 (0.46) | PSEN1MEN1KMT2AMAPTALOX5 | |
| SCHEMBL7839568 | 0.88 | PSEN1 (0.42) | PSEN1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL10536937 | 0.87 | PSEN1 (0.48) | PSEN1MEN1KMT2AMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114746430-A | Quinone-, hydroquinone-and naphthoquinone-analogues of vattinoquinone for the treatment of mitochondrial disorders | 康德生物医疗有限公司 | 2022-07-12 | — | — | CN | disclosed |