Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 9/20 | 0.67 |
| ▸ | GAK | O14976 | 1/20 | 0.67 |
| ▸ | ERBB2 | P04626 | 7/20 | 0.65 |
| ▸ | STK4 | Q13043 | 11/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28487491 | 1.00 | EGFR (0.67) | EGFRGAKERBB2STK4 | |
| SCHEMBL30390074 | 0.88 | STK4 (0.81) | EGFRGAKERBB2STK4 | |
| SCHEMBL28503961 | 0.88 | STK4 (0.81) | EGFRGAKERBB2STK4 | |
| SCHEMBL29670931 | 0.88 | STK4 (0.81) | EGFRGAKERBB2STK4 | |
| SCHEMBL29670937 | 0.87 | STK4 (0.69) | EGFRGAKERBB2STK4 | |
| Hydrochloric Acid SCHEMBL29670929 | 0.87 | STK4 (0.80) | EGFRGAKERBB2STK4 | |
| SCHEMBL28494494 | 0.87 | STK4 (0.69) | EGFRGAKERBB2STK4 | |
| Hydrochloric Acid SCHEMBL28499414 | 0.87 | STK4 (0.80) | EGFRGAKERBB2STK4 | |
| SCHEMBL30390357 | 0.86 | STK4 (0.70) | EGFRGAKERBB2STK4 | |
| SCHEMBL2131741 | 0.85 | EGFR (0.72) | EGFRGAKERBB2STK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111875539-B | Preparation method of EGFR (epidermal growth factor receptor) molecular targeted antitumor drug | 苏中药业集团股份有限公司 | 2022-06-21 | — | — | CN | disclosed |