Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | GPR6 | P46095 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28718271 | 1.00 | MAPT (0.49) | MAPTSMN1; SMN2RAB9ANPC1PKM | |
| SCHEMBL29670979 | 0.91 | MAPT (0.47) | MAPTSMN1; SMN2RAB9ANPC1NFKB1 | |
| SCHEMBL28715924 | 0.91 | MAPT (0.47) | MAPTSMN1; SMN2RAB9ANPC1NFKB1 | |
| SCHEMBL28719380 | 0.90 | MAPT (0.55) | MAPTSMN1; SMN2RAB9ANPC1PKM | |
| SCHEMBL29670976 | 0.90 | MAPT (0.55) | MAPTSMN1; SMN2RAB9ANPC1PKM | |
| SCHEMBL28722560 | 0.84 | MAPT (0.48) | MAPTSMN1; SMN2RAB9ANPC1PKM | |
| SCHEMBL29670964 | 0.84 | MAPT (0.48) | MAPTSMN1; SMN2RAB9ANPC1PKM | |
| SCHEMBL28719012 | 0.83 | MAPT (0.47) | MAPTSMN1; SMN2RAB9ANPC1PKM | |
| SCHEMBL29670991 | 0.83 | MAPT (0.47) | MAPTSMN1; SMN2RAB9ANPC1PKM | |
| SCHEMBL29670977 | 0.83 | EPHX2 (0.50) | MAPTSMN1; SMN2RAB9ANPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114276303-B | Ureido compounds or pharmaceutically acceptable salts thereof, and preparation method and application thereof | 河南大学 | 2023-09-22 | — | — | CN | disclosed |
| CN-114276303-A | Ureido compound or its medicinal salt and its preparing process and application | 河南大学 | 2022-04-05 | — | — | CN | disclosed |