Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28755158 | 1.00 | MEN1 (0.47) | MEN1KMT2AMAPTMCHR1TP53 | |
| SCHEMBL28755140 | 0.94 | MEN1 (0.48) | MEN1KMT2AMAPTTP53SMN1; SMN2 | |
| SCHEMBL29671961 | 0.94 | MEN1 (0.48) | MEN1KMT2AMAPTTP53SMN1; SMN2 | |
| SCHEMBL28755369 | 0.92 | MAPT (0.45) | MAPTMCHR1TP53HSD17B10TSHR | |
| SCHEMBL28755228 | 0.92 | MAPT (0.50) | MAPTMCHR1TP53SMN1; SMN2LMNA | |
| SCHEMBL29672019 | 0.92 | MAPT (0.50) | MAPTMCHR1TP53SMN1; SMN2LMNA | |
| SCHEMBL29672039 | 0.92 | MAPT (0.45) | MAPTMCHR1TP53HSD17B10TSHR | |
| SCHEMBL28942154 | 0.92 | MAPT (0.46) | MAPTMCHR1TP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL29671920 | 0.92 | MAPT (0.46) | MAPTMCHR1TP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL28755139 | 0.91 | PIK3CD (0.48) | MEN1KMT2AMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114573582-B | 1,2,3, 4-tetrahydropyrido [2,3-d ] pyrimidine compound and preparation method and application thereof | 沈阳药科大学 | 2023-06-16 | — | — | CN | disclosed |
| CN-114573582-A | 1,2,3, 4-tetrahydropyrido [2,3-d ] pyrimidine compound and preparation method and application thereof | 沈阳药科大学 | 2022-06-03 | — | — | CN | disclosed |