Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | RBP4 | P02753 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22926204 | 1.00 | MRGPRX4 (0.41) | MRGPRX4TAS1R3TAS1R1TAS1R2EPHX2 | |
| SCHEMBL29639652 | 0.85 | AURKA (0.44) | MRGPRX4TAS1R3TAS1R1TAS1R2EPHX2 | |
| SCHEMBL21466186 | 0.85 | AURKA (0.44) | MRGPRX4TAS1R3TAS1R1TAS1R2EPHX2 | |
| SCHEMBL2965246 | 0.84 | CA1 (0.46) | HSD17B10SLC6A3CA12CA1CA2 | |
| SCHEMBL4389273 | 0.84 | CA12 (0.52) | HSD17B10SLC6A3CA12CA1CA2 | |
| SCHEMBL184149 | 0.82 | HSD17B10 (0.54) | HSD17B10SLC6A3CA12CA1CA2 | |
| SCHEMBL475839 | 0.82 | NOTUM (0.50) | MRGPRX4EPHX2NOTUMHSD17B10CA12 | |
| SCHEMBL16729325 | 0.81 | NOTUM (0.59) | NOTUMHSD17B10CA12CA1CA2 | |
| SCHEMBL29565141 | 0.81 | NOTUM (0.59) | NOTUMHSD17B10CA12CA1CA2 | |
| SCHEMBL22089799 | 0.80 | EPHX2 (0.42) | TAS1R3TAS1R1TAS1R2EPHX2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4003974-A1 | NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES | Bayer Aktiengesellschaft (DE) | 2022-06-01 | — | — | EP | disclosed |