SCHEMBL29672174

SCHEMBL29672174

CO[C@@H](C)c1c(NC(=O)Nc2ccnc(C#N)c2)cnc2cc(F)nn12

nearest known ligand 0.81

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ MALT1 Q9UDY8 20/20 0.81
▸ BIRC3 Q13489 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18839565 1.00 MALT1 (0.81) MALT1BIRC3
SCHEMBL18839568 1.00 MALT1 (0.81) MALT1BIRC3
SCHEMBL18787743 0.90 MALT1 (1.00) MALT1BIRC3
SCHEMBL18787745 0.90 MALT1 (1.00) MALT1BIRC3
SCHEMBL18839678 0.86 MALT1 (0.66) MALT1BIRC3
SCHEMBL18839679 0.86 MALT1 (0.66) MALT1BIRC3
SCHEMBL17292930 0.85 MALT1 (0.84) MALT1BIRC3
SCHEMBL17292932 0.85 MALT1 (0.84) MALT1BIRC3
SCHEMBL18839563 0.83 MALT1 (0.62) MALT1BIRC3
SCHEMBL18839567 0.83 MALT1 (0.62) MALT1BIRC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3731848-B1 TARGETING THE CBM SIGNALOSOME COMPLEX INDUCES REGULATORY T CELLS TO INFLAME THE TUMOR MICROENVIRONMENT MASSACHUSETTS GEN HOSPITAL (US) 2026-04-15 — — EP disclosed
EP-4243812-A1 MATERIALS AND METHODS OF TREATING CANCER Monopteros Therapeutics, Inc. (US) 2023-09-20 — — EP disclosed
CN-116710089-A Materials and methods for treating cancer 莫诺泰罗斯疗法公司 2023-09-05 — — CN disclosed
WO-2022101676-A1 MATERIALS AND METHODS OF TREATING CANCER MONOPTEROS THERAPEUTICS,INC. (US) 2022-05-19 — — WO disclosed
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