SCHEMBL29672201

SCHEMBL29672201

CC(C)c1c(NC(=O)Nc2cnc(-n3nccn3)c(Cl)c2)cnc2cc(Cl)nn12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MALT1 Q9UDY8 20/20 1.00
BIRC3 Q13489 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17293008 1.00 MALT1 (1.00) MALT1BIRC3
SCHEMBL18839597 0.93 MALT1 (0.88) MALT1BIRC3
SCHEMBL18839600 0.93 MALT1 (0.88) MALT1BIRC3
SCHEMBL17292973 0.92 MALT1 (1.00) MALT1BIRC3
SCHEMBL29990125 0.92 MALT1 (0.84) MALT1BIRC3
SCHEMBL17293175 0.92 MALT1 (1.00) MALT1BIRC3
SCHEMBL17292983 0.92 MALT1 (0.84) MALT1BIRC3
SCHEMBL25500180 0.92 MALT1 (0.84) MALT1BIRC3
SCHEMBL17293152 0.92 MALT1 (0.84) MALT1BIRC3
SCHEMBL17292971 0.92 MALT1 (1.00) MALT1BIRC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3731848-B1 TARGETING THE CBM SIGNALOSOME COMPLEX INDUCES REGULATORY T CELLS TO INFLAME THE TUMOR MICROENVIRONMENT MASSACHUSETTS GEN HOSPITAL (US) 2026-04-15 EP disclosed
EP-4243812-A1 MATERIALS AND METHODS OF TREATING CANCER Monopteros Therapeutics, Inc. (US) 2023-09-20 EP disclosed
CN-116710089-A Materials and methods for treating cancer 莫诺泰罗斯疗法公司 2023-09-05 CN disclosed
WO-2022101676-A1 MATERIALS AND METHODS OF TREATING CANCER MONOPTEROS THERAPEUTICS,INC. (US) 2022-05-19 WO disclosed