Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNKSR1 | Q969H4 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 2/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | CCNC | P24863 | 5/20 | 0.41 |
| ▸ | CDK8 | P49336 | 5/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30103131 | 1.00 | CNKSR1 (0.46) | CNKSR1DPP4TTRCCNCCDK8 | |
| SCHEMBL23705853 | 1.00 | CNKSR1 (0.46) | CNKSR1DPP4TTRCCNCCDK8 | |
| SCHEMBL15507174 | 1.00 | CNKSR1 (0.46) | CNKSR1DPP4TTRCCNCCDK8 | |
| Acrylic Acid Ethyl Ester SCHEMBL23706125 | 0.94 | CNKSR1 (0.42) | CNKSR1DPP4TTRCCNCCDK8 | |
| SCHEMBL5371975 | 0.86 | DPP4 (0.47) | CNKSR1DPP4TTRCCNCCDK8 | |
| SCHEMBL5371971 | 0.86 | DPP4 (0.47) | CNKSR1DPP4TTRCCNCCDK8 | |
| SCHEMBL30645895 | 0.85 | DPP4 (0.49) | CNKSR1DPP4TTRCCNCCDK8 | |
| SCHEMBL5363535 | 0.84 | DPP4 (0.45) | CNKSR1DPP4TTRCCNCCDK8 | |
| SCHEMBL29838567 | 0.84 | DPP4 (0.45) | CNKSR1DPP4TTRCCNCCDK8 | |
| SCHEMBL5363556 | 0.84 | DPP4 (0.45) | CNKSR1DPP4TTRCCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4244213-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2023-09-20 | — | — | EP | disclosed |
| EP-4096667-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2022-12-07 | — | — | EP | disclosed |
| WO-2022103899-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2022-05-19 | — | — | WO | disclosed |