Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.48 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | CALCRL | Q16602 | 2/20 | 0.48 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.46 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 3/20 | 0.45 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.45 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29726955 | 0.93 | SLC6A2 (0.55) | SLC6A2CALCRLNMUR2NMUR1BDKRB2 | |
| SCHEMBL29506907 | 0.91 | SLC6A2 (0.53) | SLC6A2MAPK8MAPK9MAPK10CALCRL | |
| SCHEMBL31490515 | 0.91 | MAPK8 (0.54) | SLC6A2MAPK8MAPK9MAPK10CALCRL | |
| SCHEMBL31490504 | 0.90 | MAPK8 (0.52) | SLC6A2MAPK8MAPK9MAPK10CALCRL | |
| SCHEMBL29506914 | 0.90 | MAPK8 (0.51) | SLC6A2MAPK8MAPK9MAPK10CALCRL | |
| SCHEMBL29726956 | 0.89 | SLC6A2 (0.55) | SLC6A2CALCRLOPRM1OPRD1OPRK1 | |
| SCHEMBL31070215 | 0.88 | SLC6A2 (0.63) | SLC6A2CALCRLNMUR2NMUR1OPRM1 | |
| SCHEMBL29726957 | 0.88 | SLC6A2 (0.56) | SLC6A2CALCRLNMUR2NMUR1OPRM1 | |
| SCHEMBL29506913 | 0.88 | MAPK8 (0.50) | SLC6A2MAPK8MAPK9MAPK10CALCRL | |
| SCHEMBL29634976 | 0.87 | MAPK8 (0.54) | SLC6A2MAPK8MAPK9MAPK10CALCRL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4274835-A1 | COMPOUNDS COMPRISING A FIBROBLAST ACTIVATION PROTEIN LIGAND AND USE THEREOF | 3B Pharmaceuticals GmbH (DE) | 2023-11-15 | — | — | EP | disclosed |
| WO-2022148843-A1 | COMPOUNDS COMPRISING A FIBROBLAST ACTIVATION PROTEIN LIGAND AND USE THEREOF | 3B PHARMACEUTICALS GMBH (DE) | 2022-07-14 | — | — | WO | disclosed |