Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 5/20 | 0.83 |
| ▸ | ABL1 | P00519 | 14/20 | 0.73 |
| ▸ | FLT3 | P36888 | 2/20 | 0.72 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.72 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.72 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.72 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.72 |
| ▸ | SRC | P12931 | 1/20 | 0.70 |
| ▸ | KDR | P35968 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24626591 | 1.00 | KIT (0.83) | KITABL1FLT3FGFR1CYP2C9 | |
| SCHEMBL24626068 | 0.97 | KIT (0.88) | KITABL1FLT3FGFR1CYP2C9 | |
| SCHEMBL29675146 | 0.97 | KIT (0.88) | KITABL1FLT3FGFR1CYP2C9 | |
| SCHEMBL29675075 | 0.92 | KIT (0.74) | KITABL1FLT3FGFR1CYP2C9 | |
| SCHEMBL29675163 | 0.91 | KIT (0.78) | KITABL1FLT3FGFR1CYP2C9 | |
| SCHEMBL24626574 | 0.91 | KIT (0.78) | KITABL1FLT3FGFR1CYP2C9 | |
| SCHEMBL24626385 | 0.91 | KIT (0.89) | KITABL1FLT3FGFR1CYP2C9 | |
| SCHEMBL29675137 | 0.91 | KIT (0.89) | KITABL1FLT3FGFR1CYP2C9 | |
| SCHEMBL24626754 | 0.91 | KIT (0.91) | KITABL1FLT3FGFR1CYP2C9 | |
| SCHEMBL24626308 | 0.91 | KIT (1.00) | KITABL1FLT3FGFR1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022149855-A1 | HETEROARYL-ETHYNYL DERIVATIVE COMPOUND AND USE THEREOF | 주식회사 비투에스바이오 | 2022-07-14 | — | — | WO | claimed |
| WO-2022149855-A1 | HETEROARYL-ETHYNYL DERIVATIVE COMPOUND AND USE THEREOF | 주식회사 비투에스바이오 | 2022-07-14 | — | — | WO | disclosed |