Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 15/20 | 0.84 |
| ▸ | BCR | P11274 | 12/20 | 0.84 |
| ▸ | SRC | P12931 | 2/20 | 0.66 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.58 |
| ▸ | LCK | P06239 | 1/20 | 0.57 |
| ▸ | KDR | P35968 | 1/20 | 0.57 |
| ▸ | TEK | Q02763 | 1/20 | 0.57 |
| ▸ | LDLR | P01130 | 1/20 | 0.57 |
| ▸ | KIT | P10721 | 1/20 | 0.57 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.57 |
| ▸ | RAF1 | P04049 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24626536 | 1.00 | ABL1 (0.84) | ABL1BCRSRCNR2E1LCK | |
| SCHEMBL29675330 | 0.93 | ABL1 (0.83) | ABL1BCRSRCNR2E1LCK | |
| SCHEMBL3428132 | 0.91 | ABL1 (1.00) | ABL1BCRSRCNR2E1LCK | |
| SCHEMBL29515144 | 0.91 | ABL1 (1.00) | ABL1BCRSRCNR2E1LCK | |
| SCHEMBL29675033 | 0.90 | ABL1 (0.80) | ABL1BCRSRCNR2E1LCK | |
| SCHEMBL3429020 | 0.89 | ABL1 (0.87) | ABL1BCRSRCNR2E1LCK | |
| SCHEMBL29515089 | 0.89 | ABL1 (0.87) | ABL1BCRSRCNR2E1LCK | |
| SCHEMBL29675050 | 0.89 | ABL1 (0.68) | ABL1BCRSRCLCKKDR | |
| SCHEMBL24626053 | 0.87 | ABL1 (0.63) | ABL1BCRSRCLCKKDR | |
| SCHEMBL14953064 | 0.87 | ABL1 (1.00) | ABL1BCRSRCNR2E1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022149855-A1 | HETEROARYL-ETHYNYL DERIVATIVE COMPOUND AND USE THEREOF | 주식회사 비투에스바이오 | 2022-07-14 | — | — | WO | claimed |
| WO-2022149855-A1 | HETEROARYL-ETHYNYL DERIVATIVE COMPOUND AND USE THEREOF | 주식회사 비투에스바이오 | 2022-07-14 | — | — | WO | disclosed |