Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 17/20 | 0.68 |
| ▸ | BCR | P11274 | 11/20 | 0.65 |
| ▸ | LCK | P06239 | 3/20 | 0.56 |
| ▸ | KDR | P35968 | 2/20 | 0.56 |
| ▸ | TEK | Q02763 | 2/20 | 0.56 |
| ▸ | KIT | P10721 | 1/20 | 0.54 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.54 |
| ▸ | FYN | P06241 | 1/20 | 0.52 |
| ▸ | CSF1R | P07333 | 1/20 | 0.52 |
| ▸ | YES1 | P07947 | 1/20 | 0.52 |
| ▸ | LYN | P07948 | 1/20 | 0.52 |
| ▸ | HCK | P08631 | 1/20 | 0.52 |
| ▸ | FGR | P09769 | 1/20 | 0.52 |
| ▸ | SRC | P12931 | 1/20 | 0.52 |
| ▸ | CSK | P41240 | 1/20 | 0.52 |
| ▸ | BLK | P51451 | 1/20 | 0.52 |
| ▸ | BMX | P51813 | 1/20 | 0.52 |
| ▸ | SRMS | Q9H3Y6 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29675050 | 0.93 | ABL1 (0.68) | ABL1BCRLCKKDRTEK | |
| SCHEMBL24626049 | 0.93 | ABL1 (0.70) | ABL1BCRLCKKDRTEK | |
| SCHEMBL24626270 | 0.91 | ABL1 (0.68) | ABL1BCRLCKKDRTEK | |
| SCHEMBL29675239 | 0.89 | ABL1 (0.65) | ABL1BCRLCKKDRTEK | |
| SCHEMBL24626410 | 0.89 | ABL1 (0.65) | ABL1BCRLCKKDRTEK | |
| SCHEMBL29675330 | 0.89 | ABL1 (0.83) | ABL1BCRLCKKDRTEK | |
| SCHEMBL13765932 | 0.87 | ABL1 (0.68) | ABL1BCRLCKKDRTEK | |
| SCHEMBL14953340 | 0.85 | ABL1 (0.68) | ABL1BCRKITDDR1 | |
| SCHEMBL22549144 | 0.84 | ABL1 (0.70) | ABL1BCRLCKKDRTEK | |
| SCHEMBL27914925 | 0.84 | ABL1 (0.64) | ABL1BCRKITDDR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022149855-A1 | HETEROARYL-ETHYNYL DERIVATIVE COMPOUND AND USE THEREOF | 주식회사 비투에스바이오 | 2022-07-14 | — | — | WO | claimed |
| WO-2022149855-A1 | HETEROARYL-ETHYNYL DERIVATIVE COMPOUND AND USE THEREOF | 주식회사 비투에스바이오 | 2022-07-14 | — | — | WO | disclosed |