Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 12/20 | 0.72 |
| ▸ | DDR2 | Q16832 | 12/20 | 0.72 |
| ▸ | KIT | P10721 | 7/20 | 0.72 |
| ▸ | ABL1 | P00519 | 8/20 | 0.72 |
| ▸ | SRC | P12931 | 1/20 | 0.67 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.66 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.66 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.66 |
| ▸ | RET | P07949 | 2/20 | 0.65 |
| ▸ | BCR | P11274 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24626004 | 1.00 | DDR1 (0.72) | DDR1DDR2KITABL1SRC | |
| SCHEMBL2969932 | 0.92 | DDR1 (0.84) | DDR1DDR2KITABL1SRC | |
| SCHEMBL29675215 | 0.87 | ABL1 (0.65) | DDR1DDR2KITABL1SRC | |
| SCHEMBL24626405 | 0.87 | ABL1 (0.65) | DDR1DDR2KITABL1SRC | |
| SCHEMBL2964721 | 0.87 | DDR1 (0.85) | DDR1DDR2KITABL1SRC | |
| SCHEMBL2966026 | 0.87 | DDR2 (0.72) | DDR1DDR2KITABL1SRC | |
| SCHEMBL2962061 | 0.87 | DDR1 (0.82) | DDR1DDR2KITABL1SRC | |
| SCHEMBL3570799 | 0.86 | DDR1 (0.73) | DDR1DDR2KITABL1SRC | |
| SCHEMBL2966517 | 0.86 | DDR1 (0.76) | DDR1DDR2KITABL1SRC | |
| SCHEMBL2977057 | 0.85 | DDR1 (0.72) | DDR1DDR2KITABL1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022149855-A1 | HETEROARYL-ETHYNYL DERIVATIVE COMPOUND AND USE THEREOF | 주식회사 비투에스바이오 | 2022-07-14 | — | — | WO | claimed |
| WO-2022149855-A1 | HETEROARYL-ETHYNYL DERIVATIVE COMPOUND AND USE THEREOF | 주식회사 비투에스바이오 | 2022-07-14 | — | — | WO | disclosed |