Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 12/20 | 0.48 |
| ▸ | BCR | P11274 | 11/20 | 0.48 |
| ▸ | LCK | P06239 | 4/20 | 0.46 |
| ▸ | TEK | Q02763 | 3/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | CSF1R | P07333 | 3/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | YES1 | P07947 | 1/20 | 0.45 |
| ▸ | LYN | P07948 | 1/20 | 0.45 |
| ▸ | HCK | P08631 | 1/20 | 0.45 |
| ▸ | FGR | P09769 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | CSK | P41240 | 1/20 | 0.45 |
| ▸ | BLK | P51451 | 1/20 | 0.45 |
| ▸ | BMX | P51813 | 1/20 | 0.45 |
| ▸ | SRMS | Q9H3Y6 | 1/20 | 0.45 |
| ▸ | KIT | P10721 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29675209 | 1.00 | ABL1 (0.48) | ABL1BCRLCKTEKKDR | |
| SCHEMBL29675210 | 0.93 | ABL1 (0.46) | ABL1BCRLCKTEKKDR | |
| SCHEMBL29675139 | 0.93 | ABL1 (0.46) | ABL1BCRLCKTEKKDR | |
| SCHEMBL24626401 | 0.86 | ABL1 (0.54) | ABL1BCRLCKTEKKDR | |
| SCHEMBL29675250 | 0.86 | ABL1 (0.54) | ABL1BCRLCKTEKKDR | |
| SCHEMBL29675048 | 0.81 | KIT (0.47) | ABL1BCRLCKTEKKDR | |
| SCHEMBL24626351 | 0.80 | ABL1 (0.45) | ABL1BCRLCKTEKKDR | |
| SCHEMBL24626060 | 0.78 | ABL1 (0.45) | ABL1BCRLCKTEKKDR | |
| SCHEMBL24626342 | 0.77 | ABL1 (0.53) | ABL1BCRLCKTEKKDR | |
| SCHEMBL24626405 | 0.77 | ABL1 (0.65) | ABL1BCRLCKTEKKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022149855-A1 | HETEROARYL-ETHYNYL DERIVATIVE COMPOUND AND USE THEREOF | 주식회사 비투에스바이오 | 2022-07-14 | — | — | WO | claimed |
| WO-2022149855-A1 | HETEROARYL-ETHYNYL DERIVATIVE COMPOUND AND USE THEREOF | 주식회사 비투에스바이오 | 2022-07-14 | — | — | WO | disclosed |